Cytokines really should not be expressed in SI or any other molecular or 
weight-based units because preparations can vary in activity.  They should 
be expressed in units of biological activity (but no harm in giving weight 
information additionally).
Robin Barclay

Dr George Robin Barclay PhD
Consultant Clinical Scientist (Lead Scientist, SNBTS Group)
  & Honorary Senior Lecturer
SNBTS Cell Therapy Group
MRC Centre for Regenerative Medicine
The Chancellor's Building
University of Edinburgh
49 Little France Crescent
Edinburgh EH16 4SB



-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


----- Original Message ----- 
From: "Guy Hermans" <Guy.Hermans at ablynx.com>
To: <jill.omerza at novartis.com>; <cytometry at lists.purdue.edu>
Sent: Wednesday, April 29, 2009 4:32 PM
Subject: Re: [Cytometry] Conversion to SI units for cytokines


Hi J.,

Conversion of molar to mass-based concentration scales and vice versa depend 
on the molecular weight of the molecule in question - it's basic chemistry 
class, just like the 'ole highschool "weight out enough salt to make up 1 
liter of 0.25M NaCl solution" exercises.

Therefore, there cannot be a direct 'universal conversion factor' for all 
cytokines.

Guy

-----Original Message-----
From: cytometry-bounces at lists.purdue.edu 
[mailto:cytometry-bounces at lists.purdue.edu] On Behalf Of 
jill.omerza at novartis.com
Sent: Tuesday, April 28, 2009 10:02 PM
To: cytometry at lists.purdue.edu
Subject: [Cytometry] Conversion to SI units for cytokines

Does anyone know what the conversion of conventional units to SI units is
for cytokines?
e.g. What is 23 pg/mL of IL-2 ?  Is it 23 pmol/L?  Is there some kind of
conversion factor?

Best regards, Mit freundlichen Gr?ssen, Meilleures salutations,
Jill Omerza
Novartis Institutes for BioMedical Research
TS-PCS Immunotoxicology Laboratory
USEH, 406-269
Novartis Pharmaceuticals Corporation
One Health Plaza
East Hanover, NJ 07936-1080
USA
Phone: +1 862 7784045
Fax: +1 973 7818738
Email : jill.omerza at novartis.com
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