[Cytometry] question about antibodies stability

J. Paul Robinson jpr at cyto.purdue.edu
Sun Jul 19 09:27:12 EDT 2009

Dear colleagues -

I recently had about $800 antibodies shipped for a series of 
experiments. They were shipped on Saturday and the temperature over the 
weekend was nearly 100 degrees...when they were delivered on Monday 
morning they were warm. I wrote to the company and got the following 
response. I have removed the name of the company. The cost of doing the 
experiments is very high and will use valuable clinical materials. The 
company told staff that they would replace the antibodies if they didn't 
work. When we questioned them here is their response - I'd like to hear 
of others think this is accurate or acceptable.

---------company response to my email-----------------
"We understand your frustration. I would like to reassure you that we 
don't ship any orders out on Fridays. Our standard method of shipping is 
to ship Saturday evening to reduce the amount of time spent in transit. 
Also, we have successfully shipped Saturday for Monday delivery for the 
past three years, which is why we guarantee that our products will be 
stable when they arrive.

Please read below for more information {website removed]:

All [company removed] products are thawed to room temperature before 
shipping and all are shipped out at room temperature every day of the week.

Please note that the majority of antibodies are stable at room 
temperature (RT) for long periods of time. Experiments conducted at 
[company removed] show that, for antibodies left at RT, activity remains 
constant for 2 months before showing any decline. However, as a 
precautionary measure and to extend the shelf life of the antibodies, we 
ship our antibodies in refrigerated packaging which has been shown to 
provide a stable environment for antibodies in transit."

So do I risk my valuable samples to antibodies that arrive under these 
conditions? I am really not sure - perhaps my concerns are not warranted??


Paul Robinson

J. Paul Robinson
SVM Professor of Cytomics
Professor of Biomedical Engineering
Director, Purdue University Cytometry Laboratories
Past-President, International Society for Analytical Cytology
(now International Society for Advancement of Cytometry)

Purdue University Cytometry Laboratories
Bindley Bioscience Center
1203 West State Street
Discovery Park, Purdue University
West Lafayette, IN 47907-2057
Ph (765) 494 0757; Fax (765) 494 0517
email: jpr at flowcyt.cyto.purdue.edu

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