Polyclonal vs monoclonal TdT

Dalal, Bakul [Dr.][VA] Bakul.Dalal at vch.ca
Thu Nov 13 17:41:22 EST 2008

Polyclonal is better. There was a paper in mid 90's suggesting that. We
have tried single monoclonals as well as cocktails of monoclonals. They
are brighter when positive, but they miss quite a few ALLs.


Bakul Dalal MD FRCPC





From: Kirstine Oh [mailto:koh at cellnetix.com] 
Sent: Wednesday, November 12, 2008 5:18 PM
To: cyto-inbox
Subject: Polyclonal vs monoclonal TdT


I have spotted some anecdotes about polyclonal TdT being more sensitive
than monoclonal TdT, but can't find any literature on it in PubMed.
What has been everyone's experience?  How often and how much of a
difference do you think it makes?  We are trying to figure out which one
to buy for our lab.



Kirstine Oh

CellNetix Pathology and Laboratories


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