log depletion and rare events

IKaur@mdanderson.org IKaur at mdanderson.org
Thu Jun 7 12:42:14 EDT 2007

We are depleting CD138+ cells and calculating the log depletion. After 
depletion, we got 0% CD138+ cells. If we use the formula

log depletion = log (# of CD138+ cells in start fraction/ # of CD138+ 
cells in end product)

it yields no value as the denominator is zero. How does one calculate log 
depletion in such a case.

Indresh Kaur, Ph.D.
Coordinator, Flow Cytometry Lab
Department of Stem Cell Transplantation & Cellular Therapy
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