Peripheral benzodiazepine receptor agonists?

"Boros András dr." a.boros at richter.hu
Thu Feb 23 12:25:14 EST 2006


Dear Flowers,
 
Can you suggest a good and effective PBR ligand, that would roboustly affect mitochondrial membrane potential. I have tried FGIN-1-27, PK 11195, Ro54864, but they exert only weak effect and only in relatively high concentrations on the mt DYm in ECR or primary cortical cells.
 
Thanks for your kind help
 
Best regards
 
Andras Boros
Budapest
Hungary
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