Tough CLL case

Howard Ratech hratech at montefiore.org
Mon Sep 11 07:12:05 EST 2000


** High Priority **

Why not try staining for intranuclear cyclin D1 to determine if it is mantle cell
lymphoma? MCL is usually CD23-negative by tissue immunohistochemistry or dim by flow
cytometry.

Or if it is cyclin D1 positive, would anyone consider the term "atypical CLL"? Does
this have any meaning?



Howard Ratech, MD
Director of Hematopathology
Director of Molecular Pathology Lab
Montefiore Medical Center
Pathology - North 4
111 East 210th Street
Bronx, NY 10467

Telephone: 718-920-7782
FAX:           718-920-7611




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