Wich cells are il-4 producers????

gerhard nebe-von-caron Gerhard.Nebe-von-Caron at Unilever.com
Thu Feb 17 11:30:42 EST 2000


Don't the CD4 sometimes fall off under activation? Thus you might need a few
more markers. Eleven Colours might do.
Regards
Gerhard

-----Original Message-----
From:	Calman Prussin [SMTP:CPRUSSIN at niaid.nih.gov]
Sent:	Tuesday, February 15, 2000 9:59 PM
To:	Cytometry Mailing List
Subject:	RE: Wich cells are il-4 producers????


Actually, the NK T cells that are outrageous IL-4 expressers are CD4+. See
the early papers by authors Paul and/or Bendelac in mouse and our paper in
humans.
> ----------
> From: 	Samuel Lundin
> Sent: 	Tuesday, February 15, 2000 4:35 AM
> To: 	Cytometry Mailing List
> Subject: 	Re: Wich cells are il-4 producers????
> 
> 
> At 09:14 2000-02-11 -0200, Zilton Farias Meira de Vasconcelos wrote:
> >
> >Dears,
> >
> >Anybody knows about cells in the lymnphoid-gate that are CD4- and CD8-
> and
> >IL-4+ 
> >This is spleen cells of a balb/c with leishmania????
> >
> >And the cytometry reveals these cells????
> >
> >Thank's
> >
> 
> They might be NK-T cells, I presume. A large part of the T cells with NK
> receptors are CD4 and CD8 negative, and prone to IL-4 production.
> Have you checked that?
> 
> Best regards,
> 
> ============================================
> Samuel Lundin, PhD
> Dept. of Medical Microbiology and Immunology,
> Göteborg University
> Guldhedsgatan 10A, 413 46 Göteborg, Sweden
> Phone: +46-31- 826661 / 3424688
> Fax: +46-31-826976
> 
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