Kappa/lambda ratios

Tom Mchugh mchugh at pangloss.ucsf.EDU
Fri Nov 17 18:11:33 EST 1995


What are the opinions as to the importance of an inverted kappa:lambda
ratio? We sometimes see cells in peripheral blood and lymph nodes that
when phenotyped show more lambda positive cells than kappa. When the
kappa: lambda ratio is over 4 or 5 there is apparently some general
agreement that this suggests a monoclonal population. Is the same true
if the ratio is 0.25 or less?

Thanks

Tom McHugh
Department of Laboratory Medicine
University of California at San Francisco
mchugh at labmed.ucsf.edu




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